BDBM332481 4-(1-(2-chloro-6-(trifluoromethyl)benzoyl)-6-(5-oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)-1H-indazol-3-yl)-3-fluorobenzoic acid (20A)::US10196354, Example 20A::US9745265, 20A

SMILES OC(=O)c1ccc(-c2nn(C(=O)c3c(Cl)cccc3C(F)(F)F)c3cc(ccc23)-c2n[nH]c(=O)o2)c(F)c1

InChI Key InChIKey=OXMNNYUNKCFBCA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 332481   

TargetNuclear receptor ROR-gamma(Mus musculus)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM332481(4-(1-(2-chloro-6-(trifluoromethyl)benzoyl)-6-(5-ox...)
Affinity DataIC50:  120nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM332481(4-(1-(2-chloro-6-(trifluoromethyl)benzoyl)-6-(5-ox...)
Affinity DataIC50:  120nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent