BDBM332526 4-(6-(2-(azetidin-1-yl)-2- oxoethyl)-1-(2-chloro-6- (trifluoromethyl)benzoyl)- 1H-pyrazolo[4,3-b]pyridin- 3-yl)-3-fluorobenzoic acid::US10196354, Example 37B::US9745265, 37B
SMILES OC(=O)c1ccc(-c2nn(C(=O)c3c(Cl)cccc3C(F)(F)F)c3cc(CC(=O)N4CCC4)cnc23)c(F)c1
InChI Key InChIKey=MGTVGJZJGNRVRA-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 332526
Affinity DataIC50: 225nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
Affinity DataIC50: 225nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I...More data for this Ligand-Target Pair