BDBM332548 3-(4-chlorophenyl)-1-{7-[(4-fluorophenyl)carbonyl]-2,7-diazaspiro[3.5]non-2-yl}prop-2-yn-1-one::US10196369, Compound C3

SMILES Fc1ccc(cc1)C(=O)N1CCC2(CN(C2)C(=O)C#Cc2ccc(Cl)cc2)CC1

InChI Key InChIKey=CCCNVSZTHVNBBH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 332548   

TargetG-protein coupled receptor 183(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM332548(3-(4-chlorophenyl)-1-{7-[(4-fluorophenyl)carbonyl]...)
Affinity DataIC50:  12.5nMAssay Description:The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent