BindingDB logo
myBDB logout

BDBM332549 5-chloroindol-2-yl 2-[(3-fluorophenyl)methyl]-2,7-diazaspiro[3.5]non-7-yl ketone::US10196369, Compound C4

SMILES: Fc1cccc(CN2CC3(C2)CCN(CC3)C(=O)c2cc3cc(Cl)ccc3[nH]2)c1

InChI Key: InChIKey=PHZUEKYHBDIEAA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 332549   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G-protein coupled receptor 183


(Homo sapiens (Human))
BDBM332549
PNG
(5-chloroindol-2-yl 2-[(3-fluorophenyl)methyl]-2,7-...)
Show SMILES Fc1cccc(CN2CC3(C2)CCN(CC3)C(=O)c2cc3cc(Cl)ccc3[nH]2)c1
Show InChI InChI=1S/C23H23ClFN3O/c24-18-4-5-20-17(11-18)12-21(26-20)22(29)28-8-6-23(7-9-28)14-27(15-23)13-16-2-1-3-19(25)10-16/h1-5,10-12,26H,6-9,13-15H2
KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<5n/an/an/an/an/an/a



SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE

US Patent


Assay Description
The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...


US Patent US10196369 (2019)

More data for this
Ligand-Target Pair