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BDBM332560 5-chloroindol-2-yl 2-{[4-(trifluoromethyl)phenyl]methyl}-2,7-diazaspiro[3.5]non-7-yl ketone::US10196369, Compound C15

SMILES: FC(F)(F)c1ccc(CN2CC3(C2)CCN(CC3)C(=O)c2cc3cc(Cl)ccc3[nH]2)cc1

InChI Key: InChIKey=SWVOSGZCONHHLE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 332560   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G-protein coupled receptor 183


(Homo sapiens (Human))
BDBM332560
PNG
(5-chloroindol-2-yl 2-{[4-(trifluoromethyl)phenyl]m...)
Show SMILES FC(F)(F)c1ccc(CN2CC3(C2)CCN(CC3)C(=O)c2cc3cc(Cl)ccc3[nH]2)cc1
Show InChI InChI=1S/C24H23ClF3N3O/c25-19-5-6-20-17(11-19)12-21(29-20)22(32)31-9-7-23(8-10-31)14-30(15-23)13-16-1-3-18(4-2-16)24(26,27)28/h1-6,11-12,29H,7-10,13-15H2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 12.5n/an/an/an/an/an/a



SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE

US Patent


Assay Description
The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...


US Patent US10196369 (2019)

More data for this
Ligand-Target Pair