BDBM332570 (2E)-3-(4-bromophenyl)-1-{7-[(4-fluorophenyl)methyl]-2,7-diazaspiro[3.5]non-2-yl}prop-2-en-1-one::US10196369, Compound C25

SMILES Fc1ccc(CN2CCC3(CN(C3)C(=O)\C=C\c3ccc(Br)cc3)CC2)cc1

InChI Key InChIKey=LJXSHOHLYJZHAH-BJMVGYQFSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 332570   

TargetG-protein coupled receptor 183(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM332570((2E)-3-(4-bromophenyl)-1-{7-[(4-fluorophenyl)methy...)
Affinity DataIC50:  12.5nMAssay Description:The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent