BDBM332593 5-bromoindol-2-yl 7-{[4-fluoro-2-(trifluoromethyl)phenyl]carbonyl}-2,7-diazaspiro[3.5]non-2-yl ketone::US10196369, Compound C48

SMILES Fc1ccc(C(=O)N2CCC3(CN(C3)C(=O)c3cc4cc(Br)ccc4[nH]3)CC2)c(c1)C(F)(F)F

InChI Key InChIKey=XWXCJFZNBBJNJK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 332593   

TargetG-protein coupled receptor 183(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM332593(5-bromoindol-2-yl 7-{[4-fluoro-2-(trifluoromethyl)...)
Affinity DataIC50: <5nMAssay Description:The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent