BDBM332601 6-chloroindol-2-yl 7-[(4-chlorophenyl)carbonyl]-2,7-diazaspiro[3.5]non-2-yl ketone::US10196369, Compound C56

SMILES Clc1ccc(cc1)C(=O)N1CCC2(CN(C2)C(=O)c2cc3ccc(Cl)cc3[nH]2)CC1

InChI Key InChIKey=ZUTJKJXCJFHOFN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 332601   

TargetG-protein coupled receptor 183(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM332601(6-chloroindol-2-yl 7-[(4-chlorophenyl)carbonyl]-2,...)
Affinity DataIC50:  35nMAssay Description:The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent