BDBM332612 3-(4-bromophenyl)-1-{2-[(4-fluorophenyl)carbonyl]-2,7-diazaspiro[3.5]non-7-yl}prop-2-yn-1-one::US10196369, Compound C67

SMILES Fc1ccc(cc1)C(=O)N1CC2(C1)CCN(CC2)C(=O)C#Cc1ccc(Br)cc1

InChI Key InChIKey=ZIVUWXYPSLIBFE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 332612   

TargetG-protein coupled receptor 183(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM332612(3-(4-bromophenyl)-1-{2-[(4-fluorophenyl)carbonyl]-...)
Affinity DataIC50:  35nMAssay Description:The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent