BDBM332635 3-(4-fluorophenyl)-1-(2-{[4-fluoro-2-(trifluoromethyl)phenyl]methyl}-2,7-diazaspiro[3.5]non-7-yl)prop-2-yn-1-one::US10196369, Compound C90

SMILES Fc1ccc(cc1)C#CC(=O)N1CCC2(CN(Cc3ccc(F)cc3C(F)(F)F)C2)CC1

InChI Key InChIKey=ZVIBOZQUZOKTBZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 332635   

TargetG-protein coupled receptor 183(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM332635(3-(4-fluorophenyl)-1-(2-{[4-fluoro-2-(trifluoromet...)
Affinity DataIC50:  12.5nMAssay Description:The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent