BDBM332645 5-chloroindol-2-yl 9-{[3-fluoro-4-(trifluoromethyl)phenyl]carbonyl}-3,9-diazaspiro[5.5]undec-3-yl ketone::US10196369, Compound C100

SMILES Fc1cc(ccc1C(F)(F)F)C(=O)N1CCC2(CCN(CC2)C(=O)c2cc3cc(Cl)ccc3[nH]2)CC1

InChI Key InChIKey=NMSOICSGTZJVQR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 332645   

TargetG-protein coupled receptor 183(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM332645(5-chloroindol-2-yl 9-{[3-fluoro-4-(trifluoromethyl...)
Affinity DataIC50: <5nMAssay Description:The test compounds that demonstrated a corrected % activity of >=50% were defined as inhibitors of the reaction. The experimental values were normali...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent