BDBM332697 US10196374, Example 23

SMILES CCn1cc(ccc1=O)-n1ncc2cc(O[C@@H]([C@@H](NC(=O)C(C)(F)F)C(C)C)c3ccccc3)ccc12

InChI Key InChIKey=ZTIXKIDEYRTCDX-IZZNHLLZSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 332697   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM332697(US10196374, Example 23)
Affinity DataIC50:  398nMAssay Description:A reporter cell line (ChagoK1 18:7:2 s4/GRE) was established by stable transfection of the human bronchogenic carcinoma celline, ChaGo K1 (ATCC: HTB ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM332697(US10196374, Example 23)
Affinity DataEC50:  25.1nMAssay Description:A reporter cell line (ChagoK1 18:7:2 s4/GRE) was established by stable transfection of the human bronchogenic carcinoma cell line, ChaGo K1 (ATCC: HT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent