BDBM333157 US10196436, Compound 9

SMILES Cc1cccc(NC(=O)C=C)c1Nc1ncc2cc(ccc2n1)-c1cc(ccc1F)C(N)=O

InChI Key InChIKey=FNRAYBQHSJCIMJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 333157   

TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Blueprint Medicines

US Patent
LigandPNGBDBM333157(US10196436, Compound 9)
Affinity DataIC50: >1.00E+3nMAssay Description:In each well of a 384-well plate, 0.1 ng/ul of wild type FGFR-1 (Carna Biosciences, Inc.) was incubated in a total of 12.5 ul of buffer (100 mM HEPES...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Blueprint Medicines

US Patent
LigandPNGBDBM333157(US10196436, Compound 9)
Affinity DataIC50:  550nMAssay Description:In each well of a 384-well plate, 0.5 ng/ul of wild type FGFR-4 (Carna Biosciences, Inc.) was incubated in a total of 12.5 ul of buffer (100 mM HEPES...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent