BDBM333386 3-{[3-(1-Benzofuran-2- yl)imidazo[1,2-b]pyridazin- 6-yl]oxy}-N-methyl-3- phenylpropan-1-amine::US9730929, Example 7

SMILES CN(CCC(O)c1ccccc1)c1ccc2ncc(-c3cc4ccccc4o3)n2n1

InChI Key InChIKey=LENREZFKSVSWKS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 333386   

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM333386(3-{[3-(1-Benzofuran-2- yl)imidazo[1,2-b]pyridazin-...)
Affinity DataIC50:  99nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent