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BDBM333388 3-[(1R)-1-Hydroxy-2- {[3-(4-methoxy-1- benzofuran-2- yl)imidazo[1,2-b]pyridazin- 6-yl](methyl)amino}eth- yl]phenol::US9730929, Example 9

SMILES: COc1cccc2oc(cc12)-c1cnc2ccc(nn12)N(C)C[C@H](O)c1cccc(O)c1

InChI Key: InChIKey=WTQOMKMHODKEDL-KFWWJZLASA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 333388   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
mknk1 high atp


(Homo sapiens (Human))
BDBM333388
PNG
(3-[(1R)-1-Hydroxy-2- {[3-(4-methoxy-1- benzofuran-...)
Show SMILES COc1cccc2oc(cc12)-c1cnc2ccc(nn12)N(C)C[C@H](O)c1cccc(O)c1
Show InChI InChI=1S/C17H16ClN3O2S2/c18-11-3-1-2-10(6-11)8-25-17-16-20-7-12(21(16)5-4-19-17)15-14(23)13(22)9-24-15/h1-7,13-15,22-23H,8-9H2/t13-,14-,15+/m1/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 4n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...


US Patent US9730929 (2017)

More data for this
Ligand-Target Pair