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BDBM333394 1-{[3-(4-Methoxyfuro[3,2-c]pyridin-2-yl)imidazo[1,2-b]pyridazin-6-yl](methyl)amino}propan-2-ol::US9730929, Example 15

SMILES: COc1cccc2oc(cc12)-c1cnc2ccc(nn12)N(C)CC(C)O

InChI Key: InChIKey=IJFOEYYCMZROQT-OAGGEKHMSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 333394   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
mknk1 high atp


(Homo sapiens (Human))
BDBM333394
PNG
(1-{[3-(4-Methoxyfuro[3,2-c]pyridin-2-yl)imidazo[1,...)
Show SMILES COc1cccc2oc(cc12)-c1cnc2ccc(nn12)N(C)CC(C)O
Show InChI InChI=1S/C19H20N4O4S/c1-27-19(26)12-4-2-3-11(7-12)8-21-17-18-22-9-13(23(18)6-5-20-17)16-15(25)14(24)10-28-16/h2-7,9,14-16,24-25H,8,10H2,1H3,(H,20,21)/t14-,15-,16+/m1/s1
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Article
US Patent
n/an/a 10n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...


US Patent US9730929 (2017)


Article DOI: 10.1016/j.bmcl.2004.10.045
More data for this
Ligand-Target Pair