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BDBM333398 2-{[3-(1-Benzofuran-2-yl)imidazo[1,2-b]pyridazin-6-yl](methyl)amino}propan-1-ol::US9730929, Example 19

SMILES: CC(CO)N(C)c1ccc2ncc(-c3cc4ccccc4o3)n2n1

InChI Key: InChIKey=OLNWANWPIRRPDM-LUOUHOBESA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 333398   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
mknk1 high atp


(Homo sapiens (Human))
BDBM333398
PNG
(2-{[3-(1-Benzofuran-2-yl)imidazo[1,2-b]pyridazin-6...)
Show SMILES CC(CO)N(C)c1ccc2ncc(-c3cc4ccccc4o3)n2n1
Show InChI InChI=1S/C19H18F2N4O2S/c20-11-2-1-9(5-12(11)21)10-6-13(10)24-18-19-23-7-14(25(19)4-3-22-18)17-16(27)15(26)8-28-17/h1-5,7,10,13,15-17,26-27H,6,8H2,(H,22,24)/t10-,13+,15-,16-,17+/m1/s1
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PC sid
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Article
US Patent
n/an/a 47n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...


US Patent US9730929 (2017)


Article DOI: 10.1016/j.bmcl.2004.10.045
BindingDB Entry DOI: 10.7270/Q28S4S1H
More data for this
Ligand-Target Pair