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BDBM333402 2-{[3-(Furo[3,2-c]pyridin-2-yl)imidazo[1,2-b]pyridazin-6-yl](methyl)amino}-1-phenylethanol::US9730929, Example 23

SMILES: CN(CC(O)c1ccccc1)c1ccc2ncc(-c3cc4cnccc4o3)n2n1

InChI Key: InChIKey=OIHUEUIPUADELR-ZACQAIPSSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 333402   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
mknk1 high atp


(Homo sapiens (Human))
BDBM333402
PNG
(2-{[3-(Furo[3,2-c]pyridin-2-yl)imidazo[1,2-b]pyrid...)
Show SMILES CN(CC(O)c1ccccc1)c1ccc2ncc(-c3cc4cnccc4o3)n2n1
Show InChI InChI=1S/C20H19FN6O3S/c1-10-25-26-20(30-10)12-3-2-11(6-13(12)21)7-23-18-19-24-8-14(27(19)5-4-22-18)17-16(29)15(28)9-31-17/h2-6,8,15-17,28-29H,7,9H2,1H3,(H,22,23)/t15-,16-,17+/m1/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
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PC cid
PC sid
UniChem
US Patent
n/an/a 1n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...


US Patent US9730929 (2017)

More data for this
Ligand-Target Pair