BDBM333410 4-[5-(2,4-Difluorophenoxy)-2-methyl-1H-benzimidazol-6-yl]-6-methyl-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one trifluoroacetate::US9737516, Example 6

SMILES Cc1nc2cc(Oc3ccc(F)cc3F)c(cc2[nH]1)-c1cn(C)c(=O)c2[nH]ccc12

InChI Key InChIKey=DDFRPRGDKMBEEB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 333410   

TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM333410(4-[5-(2,4-Difluorophenoxy)-2-methyl-1H-benzimidazo...)
Affinity DataIC50: <100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM333410(4-[5-(2,4-Difluorophenoxy)-2-methyl-1H-benzimidazo...)
Affinity DataIC50: <100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent