BDBM333541 1-(5-tert- butylisoxazol- 3-yl)-3-(3- (7-(2-(4-(2- hydroxyethyl) piperazin-1- yl)ethoxy)-6- methoxy- quinazolin- 4- ylthio)phenyl) urea::US9730937, Example 84
SMILES COc1cc2c(Sc3cccc(NC(=O)Nc4cc(on4)C(C)(C)C)c3)ncnc2cc1OCCN1CCC(CCO)CC1
InChI Key InChIKey=YYYPPBRIXIEAIL-UHFFFAOYSA-N
Data 3 Kd
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 333541
Affinity DataKd: <250nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Ambit Biosciences
US Patent
Ambit Biosciences
US Patent
Affinity DataKd: 375nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
Affinity DataKd: 375nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair