BDBM333673 1-(3- methoxy-4- (trifluoromethyl) phenyl)- 3-(3-(6- methoxy-7-(2- methoxyethoxy) quinazolin-4- yloxy)phenyl) urea::US9730937, Example 223
SMILES COCCOc1cc2ncnc(Oc3cccc(NC(=O)Nc4ccc(c(OC)c4)C(F)(F)F)c3)c2cc1OC
InChI Key InChIKey=TXLPFIVDCVNKCY-UHFFFAOYSA-N
Data 3 Kd
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 333673
Affinity DataKd: 375nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Ambit Biosciences
US Patent
Ambit Biosciences
US Patent
Affinity DataKd: 750nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
Affinity DataKd: >1.00E+3nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair