BDBM333836 1-(5-(1,3- difluoro- 2-methylpropan- 2- yl)isoxazol-3-yl)- 3- (3-(7-ethoxy-6- methoxy- quinazolin- 4-yloxy)phenyl) urea::US9730937, Example 386
SMILES CCOc1cc2ncnc(Oc3cccc(NC(=O)Nc4cc(on4)C(C)(CF)CF)c3)c2cc1OC
InChI Key InChIKey=JYNHRFKRDRLWMM-UHFFFAOYSA-N
Data 3 Kd
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 333836
Affinity DataKd: <250nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Ambit Biosciences
US Patent
Ambit Biosciences
US Patent
Affinity DataKd: <250nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
Affinity DataKd: <250nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair