BDBM333891 US9730940, Compound 1-44::[(3S,4S) and (3R,4R)]-tert-butyl 3-{[9-ethyl-8-(2- methylpyrimidin-5-yl)-9H- purin-6-yl]oxy}-4- fluoropyrrolidine-1-carboxylate

SMILES CCn1c(nc2c(OC3CN(CC3F)C(=O)OC(C)(C)C)ncnc12)-c1cnc(C)nc1

InChI Key InChIKey=HFNOQOKWCDZPFP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 333891   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM333891(US9730940, Compound 1-44 | [(3S,4S) and (3R,4R)]-t...)
Affinity DataIC50:  3.30nMAssay Description:The PI3-Kinase biochemical assay was optimized using the HTRF kit provided by Upstate (Millipore). The assay kit contains six reagents: 1) 4× Reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent