BDBM333936 8-(1-ethyl-5-methyl-1H-pyrazol- 4-yl)-9-methyl-6-({(3S)-1-[(1- methyl-1H-pyrazol-3- yl)carbonyl]pyrrolidin-3- yl}oxy)-9H-purine::US9730940, Compound 2-37
SMILES CCn1ncc(c1C)-c1nc2c(O[C@H]3CCN(C3)C(=O)c3ccn(C)n3)ncnc2n1C
InChI Key InChIKey=DXCIMHKGLMJSQK-AWEZNQCLSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 333936
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 2.20nMAssay Description:The PI3-Kinase biochemical assay was optimized using the HTRF kit provided by Upstate (Millipore). The assay kit contains six reagents: 1) 4× Reactio...More data for this Ligand-Target Pair