BDBM333995 (S)-1-(3-((8-(2-(tert- butyl)thiazol-5-yl)-9-methyl-9H- purin-6-yl)oxy)pyrrolidin-1- yl)propan-1-one::US9730940, Compound 2-96

SMILES CCC(=O)N1CCC(C1)Oc1ncnc2n(C)c(nc12)-c1cnc(s1)C(C)(C)C

InChI Key InChIKey=KZVLUYWRJIUXEP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 333995   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM333995((S)-1-(3-((8-(2-(tert- butyl)thiazol-5-yl)-9-methy...)
Affinity DataIC50:  1.60nMAssay Description:The PI3-Kinase biochemical assay was optimized using the HTRF kit provided by Upstate (Millipore). The assay kit contains six reagents: 1) 4× Reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent