BDBM334144 (3S)-N-cyclohexyl-3-{[8-(1- ethyl-5-methyl-1H-pyrazol-4- yl)-9-methyl-9H-purin-6- yl]oxy}pyrrolidine-1- carboxamide::US9730940, Compound 5-1
SMILES CCn1ncc(c1C)-c1nc2c(O[C@H]3CCN(C3)C(=O)NC3CCCCC3)ncnc2n1C
InChI Key InChIKey=VYMKJBBLBLRTNZ-KRWDZBQOSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 334144
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 230nMAssay Description:The PI3-Kinase biochemical assay was optimized using the HTRF kit provided by Upstate (Millipore). The assay kit contains six reagents: 1) 4× Reactio...More data for this Ligand-Target Pair