BDBM334144 (3S)-N-cyclohexyl-3-{[8-(1- ethyl-5-methyl-1H-pyrazol-4- yl)-9-methyl-9H-purin-6- yl]oxy}pyrrolidine-1- carboxamide::US9730940, Compound 5-1

SMILES CCn1ncc(c1C)-c1nc2c(O[C@H]3CCN(C3)C(=O)NC3CCCCC3)ncnc2n1C

InChI Key InChIKey=VYMKJBBLBLRTNZ-KRWDZBQOSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 334144   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM334144((3S)-N-cyclohexyl-3-{[8-(1- ethyl-5-methyl-1H-pyra...)
Affinity DataIC50:  230nMAssay Description:The PI3-Kinase biochemical assay was optimized using the HTRF kit provided by Upstate (Millipore). The assay kit contains six reagents: 1) 4× Reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent