BDBM334149 1-(3-{3-[1-(4-Amino-3-methyl-1H- pyrazolo[3,4-d]pyrimidin-1- yl)ethyl]-5,6-dichloro-2- methoxyphenyl}azetidin-1-yl)-2- methylpropan-2-ol::US10376513, Example 303::US10646492, Example 303::US11433071, Example 303::US9730939, Example 303
SMILES COc1c(cc(Cl)c(Cl)c1C1CN(CC(C)(C)O)C1)C(C)n1nc(C)c2c(N)ncnc12
InChI Key InChIKey=YEPQYHYCTPHTBV-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 334149
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Incyte Holdings
US Patent
Incyte Holdings
US Patent
Affinity DataIC50: <10nMAssay Description:[γ-33P]ATP (10 mCi/mL) was purchased from PerkinElmer (Waltham, Mass.). Lipid kinase substrate, D-myo-Phosphatidylinositol 4,5-bisphosphate (Ptd...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Incyte Holdings
US Patent
Incyte Holdings
US Patent
Affinity DataIC50: <10nMAssay Description:The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Incyte Holdings
US Patent
Incyte Holdings
US Patent
Affinity DataIC50: <10nMAssay Description:The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 uL. Inhibitors wer...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Incyte Holdings
US Patent
Incyte Holdings
US Patent
Affinity DataIC50: <10nMAssay Description:[γ-33P]ATP (10 mCi/mL) was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase substrate, D-myo-Phosphatidylinositol 4,5-bisphosphate (Pt...More data for this Ligand-Target Pair