BDBM334221 US9730940, Compound 9-1::US9730940, Compound 9-2::cis-tert-butyl [(1S,3R)-3-{[8-(1- ethyl-5-methyl-1H-pyrazol-4- yl)-9-methyl-9H-purin-6- yl]oxy}cyclopentyl]carbamate
SMILES CCn1ncc(c1C)-c1nc2c(OC3CCC(C3)NC(=O)OC(C)(C)C)ncnc2n1C
InChI Key InChIKey=PRFSFXUBDCSISV-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 334221
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 140nMAssay Description:The PI3-Kinase biochemical assay was optimized using the HTRF kit provided by Upstate (Millipore). The assay kit contains six reagents: 1) 4× Reactio...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 400nMAssay Description:The PI3-Kinase biochemical assay was optimized using the HTRF kit provided by Upstate (Millipore). The assay kit contains six reagents: 1) 4× Reactio...More data for this Ligand-Target Pair