BDBM334268 US9730940, Compound 15-3::tert-butyl (3S)-3-({8- [(cyclopropylmethyl)carbamoyl]- 9-ethyl-9H-purin-6- yl}oxy)pyrrolidine-1- carboxylate

SMILES CCn1c(nc2c(O[C@H]3CCN(C3)C(=O)OC(C)(C)C)ncnc12)C(=O)NCC1CC1

InChI Key InChIKey=KZMMKGVLAUBDLD-AWEZNQCLSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 334268   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM334268(US9730940, Compound 15-3 | tert-butyl (3S)-3-({8- ...)
Affinity DataIC50:  150nMAssay Description:The PI3-Kinase biochemical assay was optimized using the HTRF kit provided by Upstate (Millipore). The assay kit contains six reagents: 1) 4× Reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent