BDBM334268 US9730940, Compound 15-3::tert-butyl (3S)-3-({8- [(cyclopropylmethyl)carbamoyl]- 9-ethyl-9H-purin-6- yl}oxy)pyrrolidine-1- carboxylate
SMILES CCn1c(nc2c(O[C@H]3CCN(C3)C(=O)OC(C)(C)C)ncnc12)C(=O)NCC1CC1
InChI Key InChIKey=KZMMKGVLAUBDLD-AWEZNQCLSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 334268
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 150nMAssay Description:The PI3-Kinase biochemical assay was optimized using the HTRF kit provided by Upstate (Millipore). The assay kit contains six reagents: 1) 4× Reactio...More data for this Ligand-Target Pair