BDBM33432 1-[5-amino-3-(4-methylphenyl)-1,2,4-triazol-1-yl]-2-phenylethanone::1-[5-amino-3-(p-tolyl)-1,2,4-triazol-1-yl]-2-phenyl-ethanone::1-[5-azanyl-3-(4-methylphenyl)-1,2,4-triazol-1-yl]-2-phenyl-ethanone::3-(4-methylphenyl)-1-(phenylacetyl)-1H-1,2,4-triazol-5-amine::MLS000049087::SMR000074381::cid_974955

SMILES Cc1ccc(cc1)-c1nc(N)n(n1)C(=O)Cc1ccccc1

InChI Key InChIKey=RLMDHZHCYICOEW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 33432   

TargetCoagulation factor XII(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM33432(1-[5-amino-3-(4-methylphenyl)-1,2,4-triazol-1-yl]-...)
Affinity DataIC50:  6.26E+3nMpH: 7.4 T: 2°CAssay Description:HTS was performed on a total of 33,068 compounds of the MLSCN library, 23,017 of which were not in the mixture HTS plates used previously. These comp...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCoagulation factor XII(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM33432(1-[5-amino-3-(4-methylphenyl)-1,2,4-triazol-1-yl]-...)
Affinity DataIC50:  6.26E+3nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProthrombin(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM33432(1-[5-amino-3-(4-methylphenyl)-1,2,4-triazol-1-yl]-...)
Affinity DataIC50:  1.82E+3nMpH: 7.5 T: 2°CAssay Description:HTS was performed using 217,350 compounds of the MLSCN library individually plated into 10ul 1536 compound plates at a concentration of 2.5 mM each, ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay