BDBM334340 1-(2,3-Dichloro-4-((2-((3-(cyclopropylsulfonyl)phenyl)amino)pyrimidin-4-yl)oxy)phenyl)-3-(3-isopropyl-1-(p-tolyl)-1H-pyrazol-5-yl)urea::US9732063, Example 24

SMILES CC(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4cccc(c4)S(=O)(=O)C4CC4)n3)c(Cl)c2Cl)n(n1)-c1ccc(C)cc1

InChI Key InChIKey=VOYFMGMBXYOYAM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 334340   

TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
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US Patent
LigandPNGBDBM334340(1-(2,3-Dichloro-4-((2-((3-(cyclopropylsulfonyl)phe...)
Affinity DataIC50:  117nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent