BDBM334342 S,S-Dimethyl-N-(3-(4-(2,3-dichloro-4-(3-(3-isopropyl-1-(p-tolyl)-1H-pyrazol-5-yl)ureido)-phenoxy)pyrimidin-2-yl)amino)-5-methoxyphenyl)sulfoximine::US9732063, Example 26

SMILES COc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(nn4-c4ccc(C)cc4)C(C)C)c(Cl)c3Cl)n2)cc(c1)N=S(C)(C)=O

InChI Key InChIKey=OXEVYWPQJZHURB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 334342   

TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
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US Patent
LigandPNGBDBM334342(S,S-Dimethyl-N-(3-(4-(2,3-dichloro-4-(3-(3-isoprop...)
Affinity DataIC50:  426nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent