BDBM334749 US11040966, Example 4.107::US9732075, Example 4.107::[(2S,3S)-2-(5-Chloro-6-methyl-1H-benzoimidazol-2-yl)-3-methyl-pyrrolidin-1-yl]-(2-fluoro-6-pyridin-3-yl-phenyl)-methanone

SMILES C[C@H]1CCN([C@@H]1c1nc2cc(Cl)c(C)cc2[nH]1)C(=O)c1c(F)cccc1-c1cccnc1

InChI Key InChIKey=SECISWKEZAHASH-PSLXWICFSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 334749   

TargetOrexin receptor type 2(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM334749(US11040966, Example 4.107 | US9732075, Example 4.1...)
Affinity DataIC50:  1.76E+3nMAssay Description:Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM334749(US11040966, Example 4.107 | US9732075, Example 4.1...)
Affinity DataIC50:  47nMAssay Description:Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent