BDBM3354 2,2 -Diselenobis[N,1-dimethyl-1H-indole-3-carboxamide]::N,1-dimethyl-2-{[1-methyl-3-(methylcarbamoyl)-1H-indol-2-yl]diselanyl}-1H-indole-3-carboxamide::diselenobis(1H-indole) deriv. 23

SMILES CNC(=O)c1c([Se][Se]c2c(C(=O)NC)c3ccccc3n2C)n(C)c2ccccc12

InChI Key InChIKey=KKTAXCWCKSLCHF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 3354   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3354(2,2 -Diselenobis[N,1-dimethyl-1H-indole-3-carboxam...)
Affinity DataIC50:  6.10E+3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase transforming protein Src(Avian sarcoma virus)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3354(2,2 -Diselenobis[N,1-dimethyl-1H-indole-3-carboxam...)
Affinity DataIC50:  400nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3354(2,2 -Diselenobis[N,1-dimethyl-1H-indole-3-carboxam...)
Affinity DataIC50:  4.70E+3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed