BDBM335405 US10717738, Example 264::US9732085, 264::methyl{4-[4-chloro-2-(1-{4-[5-chloro-2-(1H-tetrazol-1-yl)phenyl]-2-oxo-1(2H)-pyridinyl]-3-methoxypropyl)-1H-imidazol-5-yl}phenyl}carbamate

SMILES COCCC(c1nc(Cl)c([nH]1)-c1ccc(NC(=O)OC)cc1)n1ccc(cc1=O)-c1cc(Cl)ccc1-n1cnnn1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 335405   

TargetCoagulation factor XI(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM335405(US10717738, Example 264 | US9732085, 264 | methyl{...)
Affinity DataIC50:  6.10nMAssay Description:Human Factor XIa activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6000, 50 mM HEPES-NaOH (pH7.4) wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM335405(US10717738, Example 264 | US9732085, 264 | methyl{...)
Affinity DataIC50:  6.10nMAssay Description:Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent