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BDBM335442 Cyclopropylmethyl-(4-piperazin-1-yl-pyrimidin-2-yl)-amine::US9732087, 66

SMILES: C(Nc1nccc(n1)N1CCNCC1)C1CC1

InChI Key: InChIKey=WXWLLLPFQQBISE-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 335442   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H4 receptor


(Homo sapiens (Human))
BDBM335442
PNG
(Cyclopropylmethyl-(4-piperazin-1-yl-pyrimidin-2-yl...)
Show SMILES C(Nc1nccc(n1)N1CCNCC1)C1CC1
Show InChI InChI=1S/C12H19N5/c1-2-10(1)9-15-12-14-4-3-11(16-12)17-7-5-13-6-8-17/h3-4,10,13H,1-2,5-9H2,(H,14,15,16)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
12.2n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA N.V.

US Patent


Assay Description
Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...


US Patent US9732087 (2017)

More data for this
Ligand-Target Pair