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BDBM335445 4-(3-Aminoazetidin-1-yl)-N-(2-methylpropyl)pyrimidin-2-amine::US9732087, 89

SMILES: CC(C)CNc1nccc(n1)N1CC(N)C1

InChI Key: InChIKey=SVTHLINSGZJXDW-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 335445   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H4 receptor


(Homo sapiens (Human))
BDBM335445
PNG
(4-(3-Aminoazetidin-1-yl)-N-(2-methylpropyl)pyrimid...)
Show SMILES CC(C)CNc1nccc(n1)N1CC(N)C1
Show InChI InChI=1S/C11H19N5/c1-8(2)5-14-11-13-4-3-10(15-11)16-6-9(12)7-16/h3-4,8-9H,5-7,12H2,1-2H3,(H,13,14,15)
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KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
26.2n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA N.V.

US Patent


Assay Description
Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...


US Patent US9732087 (2017)


Article DOI: 10.1021/jm060807n
More data for this
Ligand-Target Pair