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BDBM335555 US9737525, Compound MIND4-17-3

SMILES: [O-][N+](=O)c1ccc(Sc2nnc(COc3ccccc3)[nH]2)nc1

InChI Key: InChIKey=VQKWEANLOVSOSL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 335555   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
NAD-dependent deacetylase sirtuin 2


(Homo sapiens (Human))
BDBM335555
PNG
(US9737525, Compound MIND4-17-3)
Show SMILES [O-][N+](=O)c1ccc(Sc2nnc(COc3ccccc3)[nH]2)nc1
Show InChI InChI=1S/C14H11N5O3S/c20-19(21)10-6-7-13(15-8-10)23-14-16-12(17-18-14)9-22-11-4-2-1-3-5-11/h1-8H,9H2,(H,16,17,18)
PDB
MMDB

NCI pathway
KEGG

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
n/an/a>5.00E+7n/an/an/an/an/an/a



The General Hospital Corporation; The Regents of the University of California

US Patent


Assay Description
Modulation of sirtuin activity by compounds was assessed using the Flour de Lys fluorescent biochemical assay in a 96-well format as described (Outei...


US Patent US9737525 (2017)


Article DOI: 10.1021/jm060727j
More data for this
Ligand-Target Pair