BDBM335579 5-((4-aminopiperidin-1-yl)methyl)-N-(3-(5-cyclohexyl-1,2,4-oxadiazol-3-yl)phenyl)pyrrolo[2,1-f][1,2,4]triazin-4-amine::US9737542, Example 22

SMILES NC1CCN(Cc2ccn3ncnc(Nc4cccc(c4)-c4noc(n4)C4CCCCC4)c23)CC1

InChI Key InChIKey=ACFTUGYJRWOZNI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 335579   

TargetAP2-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM335579(5-((4-aminopiperidin-1-yl)methyl)-N-(3-(5-cyclohex...)
Affinity DataIC50:  14nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent