BDBM335594 3-((5-((4-aminopiperidin-1-yl)methyl)pyrrolo[2,1-f][1,2,4]triazin-4-yl)amino)-5-(5-isopropyl-1,2,4-oxadiazol-3-yl)phenol::US9737542, Example 37

SMILES CC(C)c1nc(no1)-c1cc(O)cc(Nc2ncnn3ccc(CN4CCC(N)CC4)c23)c1

InChI Key InChIKey=IUNSEBJPIREZQQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 335594   

TargetAP2-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM335594(3-((5-((4-aminopiperidin-1-yl)methyl)pyrrolo[2,1-f...)
Affinity DataIC50:  5.5nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent