BDBM335619 5-((4-aminopiperidin-1-yl)methyl)-N-(3-isopropoxy-5-(2-isopropyl-2H-tetrazol-5-yl)phenyl)pyrrolo[2,1-f][1,2,4]triazin-4-amine::US9737542, Example 62

SMILES CC(C)Oc1cc(Nc2ncnn3ccc(CN4CCC(N)CC4)c23)cc(c1)-c1nnn(n1)C(C)C

InChI Key InChIKey=VBPUWVVGXJGULI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 335619   

TargetAP2-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM335619(5-((4-aminopiperidin-1-yl)methyl)-N-(3-isopropoxy-...)
Affinity DataIC50:  550nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent