BDBM335818 2-[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]-2-pyrrolo- [1,2-a]pyrazin-1-yl- acetamide::US11065253, Example 348::US9732094, Example 348
SMILES NC(=O)C(c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1nccn2cccc12
InChI Key InChIKey=LUQVTTRAGKZSBB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 335818
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Patent
US Patent
Merck Patent
US Patent
Affinity DataKi: 1.25E+4nMAssay Description:The patch-clamp measurement was carried out at room temperature in whole-cell configuration on human embryonic kidney cells (HEK293) which have been ...More data for this Ligand-Target Pair
Affinity DataIC50: <3nMAssay Description:The kinase assay was carried out in streptavidin-coated 348-well microtitre flashplates. To this end, 1.5 μg of DNA-PK/protein complex and 100 n...More data for this Ligand-Target Pair
Affinity DataIC50: <3nMAssay Description:The kinase assay was carried out in streptavidin-coated 348-well microtitre flashplates. To this end, 1.5 ug of DNA-PK/protein complex and 100 ng of ...More data for this Ligand-Target Pair