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BDBM336140 US9738658, Example 22

SMILES: CCCn1ccc2cc(cc(C3CC3)c12)N(CCO[Si](C)(C)C(C)(C)C)C(=O)c1c(Cl)ncnc1Cl

InChI Key: InChIKey=XNDUBLDQKWAFNR-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 336140   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
hdgat le


(Homo sapiens (Human))
BDBM336140
PNG
(US9738658, Example 22)
Show SMILES CCCn1ccc2cc(cc(C3CC3)c12)N(CCO[Si](C)(C)C(C)(C)C)C(=O)c1c(Cl)ncnc1Cl
Show InChI InChI=1S/C27H36Cl2N4O2Si/c1-7-11-32-12-10-19-15-20(16-21(23(19)32)18-8-9-18)33(13-14-35-36(5,6)27(2,3)4)26(34)22-24(28)30-17-31-25(22)29/h10,12,15-18H,7-9,11,13-14H2,1-6H3
UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1.80n/an/an/an/an/an/a



GlaxoSmithKline LLC

US Patent


Assay Description
For inhibition of triacylglycerol product formation, 11 uL reactions were run in white Polyplate-384 (PerkinElmer6007300) starting with a 30 minute p...


US Patent US9738658 (2017)

More data for this
Ligand-Target Pair