BindingDB logo
myBDB logout

BDBM336236 US9744172, Compound UNC00000481A

SMILES: CNc1ncc2c(nn(CC3CCC(N)CC3)c2n1)-c1ccc(cc1)C(=O)OC

InChI Key: InChIKey=IUYPJRXGQIEYPD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 336236   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM336236
PNG
(US9744172, Compound UNC00000481A)
Show SMILES CNc1ncc2c(nn(CC3CCC(N)CC3)c2n1)-c1ccc(cc1)C(=O)OC
Show InChI InChI=1S/C21H26N6O2/c1-23-21-24-11-17-18(14-5-7-15(8-6-14)20(28)29-2)26-27(19(17)25-21)12-13-3-9-16(22)10-4-13/h5-8,11,13,16H,3-4,9-10,12,22H2,1-2H3,(H,23,24,25)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 55n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
The ectopic expression of Mer receptor tyrosine kinase (Mer) has been identified as a tumor cell survival gene product in Acute Lymphoblastic Leukemi...


US Patent US9744172 (2017)

More data for this
Ligand-Target Pair