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BDBM336239 US9744172, Compound UNC00000487A

SMILES: CNc1ncc2c(nn(CC3CCC(N)CC3)c2n1)-c1ccc(OCc2ccccc2)cc1

InChI Key: InChIKey=XOWFQQYOZPCGSO-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 336239   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM336239
PNG
(US9744172, Compound UNC00000487A)
Show SMILES CNc1ncc2c(nn(CC3CCC(N)CC3)c2n1)-c1ccc(OCc2ccccc2)cc1
Show InChI InChI=1S/C26H30N6O/c1-28-26-29-15-23-24(31-32(25(23)30-26)16-18-7-11-21(27)12-8-18)20-9-13-22(14-10-20)33-17-19-5-3-2-4-6-19/h2-6,9-10,13-15,18,21H,7-8,11-12,16-17,27H2,1H3,(H,28,29,30)
PDB
MMDB

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KEGG

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PC cid
PC sid
UniChem
US Patent
n/an/a 55n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
The ectopic expression of Mer receptor tyrosine kinase (Mer) has been identified as a tumor cell survival gene product in Acute Lymphoblastic Leukemi...


US Patent US9744172 (2017)

More data for this
Ligand-Target Pair