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BDBM336240 US9744172, Compound UNC00000394A

SMILES: CNc1ncc2c(nn(CC3CCC(N)CC3)c2n1)-c1ccc2OCOc2c1

InChI Key: InChIKey=BINNRFSDLJQDGB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 336240   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM336240
PNG
(US9744172, Compound UNC00000394A)
Show SMILES CNc1ncc2c(nn(CC3CCC(N)CC3)c2n1)-c1ccc2OCOc2c1
Show InChI InChI=1S/C20H24N6O2/c1-22-20-23-9-15-18(13-4-7-16-17(8-13)28-11-27-16)25-26(19(15)24-20)10-12-2-5-14(21)6-3-12/h4,7-9,12,14H,2-3,5-6,10-11,21H2,1H3,(H,22,23,24)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
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PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
The ectopic expression of Mer receptor tyrosine kinase (Mer) has been identified as a tumor cell survival gene product in Acute Lymphoblastic Leukemi...


US Patent US9744172 (2017)

More data for this
Ligand-Target Pair