BindingDB logo
myBDB logout

BDBM336251 US9744172, Compound UNC00000480A

SMILES: CNc1ncc2c(nn(CC3CCC(N)CC3)c2n1)-c1cnc[nH]1

InChI Key: InChIKey=IREROJQVUXODAU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 336251   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM336251
PNG
(US9744172, Compound UNC00000480A)
Show SMILES CNc1ncc2c(nn(CC3CCC(N)CC3)c2n1)-c1cnc[nH]1
Show InChI InChI=1S/C16H22N8/c1-18-16-20-6-12-14(13-7-19-9-21-13)23-24(15(12)22-16)8-10-2-4-11(17)5-3-10/h6-7,9-11H,2-5,8,17H2,1H3,(H,19,21)(H,18,20,22)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
The ectopic expression of Mer receptor tyrosine kinase (Mer) has been identified as a tumor cell survival gene product in Acute Lymphoblastic Leukemi...


US Patent US9744172 (2017)

More data for this
Ligand-Target Pair