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BDBM336254 US9744172, Compound UNC00000411A

SMILES: CNc1ncc2c(nn(CC3CC[C@H](N)CC3)c2n1)-c1cnc(N)nc1

InChI Key: InChIKey=CGKNPSHGUDGPBM-KGJGHSEXSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 336254   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM336254
PNG
(US9744172, Compound UNC00000411A)
Show SMILES CNc1ncc2c(nn(CC3CC[C@H](N)CC3)c2n1)-c1cnc(N)nc1
Show InChI InChI=1S/C17H23N9/c1-20-17-23-8-13-14(11-6-21-16(19)22-7-11)25-26(15(13)24-17)9-10-2-4-12(18)5-3-10/h6-8,10,12H,2-5,9,18H2,1H3,(H2,19,21,22)(H,20,23,24)/t10?,12-
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
The ectopic expression of Mer receptor tyrosine kinase (Mer) has been identified as a tumor cell survival gene product in Acute Lymphoblastic Leukemi...


US Patent US9744172 (2017)

More data for this
Ligand-Target Pair