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BDBM336263 US9744172, Compound UNC582A

SMILES: CCCCNc1ncc2c(nn(CC3CC[C@H](N)CC3)c2n1)-c1ccc(cc1)N1CCOCC1

InChI Key: InChIKey=WUUJHWOTTCPVIY-QSNACTPISA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 336263   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM336263
PNG
(US9744172, Compound UNC582A)
Show SMILES CCCCNc1ncc2c(nn(CC3CC[C@H](N)CC3)c2n1)-c1ccc(cc1)N1CCOCC1
Show InChI InChI=1S/C26H37N7O/c1-2-3-12-28-26-29-17-23-24(20-6-10-22(11-7-20)32-13-15-34-16-14-32)31-33(25(23)30-26)18-19-4-8-21(27)9-5-19/h6-7,10-11,17,19,21H,2-5,8-9,12-16,18,27H2,1H3,(H,28,29,30)/t19?,21-
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a<10n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
The ectopic expression of Mer receptor tyrosine kinase (Mer) has been identified as a tumor cell survival gene product in Acute Lymphoblastic Leukemi...


US Patent US9744172 (2017)

More data for this
Ligand-Target Pair