BindingDB logo
myBDB logout

BDBM336284 US9744172, Compound UNC1067A

SMILES: O[C@H]1CCC(CC1)n1nc(-c2ccc(cc2)N2CCOCC2)c2cnc(NCC(F)(F)F)nc12

InChI Key: InChIKey=YLOANLBVLPVTOV-WEBLMRDCSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 336284   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM336284
PNG
(US9744172, Compound UNC1067A)
Show SMILES O[C@H]1CCC(CC1)n1nc(-c2ccc(cc2)N2CCOCC2)c2cnc(NCC(F)(F)F)nc12
Show InChI InChI=1S/C23H27F3N6O2/c24-23(25,26)14-28-22-27-13-19-20(15-1-3-16(4-2-15)31-9-11-34-12-10-31)30-32(21(19)29-22)17-5-7-18(33)8-6-17/h1-4,13,17-18,33H,5-12,14H2,(H,27,28,29)/t17?,18-
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 55n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
The ectopic expression of Mer receptor tyrosine kinase (Mer) has been identified as a tumor cell survival gene product in Acute Lymphoblastic Leukemi...


US Patent US9744172 (2017)

More data for this
Ligand-Target Pair